HiThis is something which is very much personal preference and could prove quite a lively topic. I have driven over 500,000 miles in cars and have only had one puncture.
Here's where I show my age, back in my Triumph Bonneville days (£396 brand new and made at Meridan!) a new product came onto the market called Tyre weld, intended to seal and re-inflate a tyre, it wasthe predessesor of all the tins of goo. It was used mainly by trail bike riders as an insurance, in case they got a puncture. I bought a can but gratefully never got round to using it.
I have looked at the website (video did not work) the plugger may be legal in the US but have you checked if it is over here? If it is legal to use over here, sods law says the puncture would happen in the dark and rain and if you were able to find the hole it would be in the most awkward place possible. Putting you at risk, laying under the cartrying to align the applicator to the inside tread of a rear tyre with your legs sticking out for someone to run over.
I went for a spare tyre so cannot comment with authority of the efficiency of the aerosol approach. Two work mates had punctures, tried the goo and it did not work, one would not seal, the other could not re-inflate his flat tyre due to the limited ability of the compressor (lost rim seal). My son damaged a tyre on his car which could not be repaired and was taken with wheel to a tyre depot to get a VERY expensive tyre fitted and much time lost.
My spare and its additional storage boxes use up quite a lot of boot height, but I do not fill my boot that often.Another option woud be to buy a spare wheel and have a tyre fitted thenget a jack and storage bag to hold all of them. Then you would have more options either to rely on the plugger (if legal) or goo, or to load the bagged spare wheel upright in the boot which takes up less space. That way if you don't want the hassle of changing a wheel you could try the goo, and if that failed rather than be stranded still have the option of a wheel change.
I travel abroad, if you do the same you would need to check up about the plugger in each country you pass through. An old motorbike habit that I still have is to check my tyres for stones and nails each weekend, prevention is better than cure.
I expect there will be others saying I am wrong but it is individual choice, you could always take the bagged spare out of the boot if you needed the space and then rely on the compressor.